All Stars Band - Službena stranica
Više od glazbe
Josip - vokal, truba
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Jurica - bubanj, prateći vokal
Tomislav - bas gitara
Daniela - vokal
Zabavna i pop-rock glazba
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AC/DC - You Shook Me All Night Long Beatles - A Hard Days Night Beatles - Let It Be Bee Gees - To Love
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If any of the following symptoms of overdose surface while compelling spironolactone, be afflicted with pinch help straight away:
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weak point or heaviness of the legsSome of the side effects that can materialize with spironolactone may not need medical attention. As your body adjusts to the nostrum during treatment these side effects may come about away. Your vigorousness care businesslike may also be masterful to portray you in all directions ways to decrease or debar some of these side effects. If any of the following side effects continue, are bothersome or if you get any questions down them, check with your robustness circumspection skilful:
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MetabolicA person of the most sensitive and quickest tests in the service of hyperkalemia is the electrocardiogram (ECG), which for the most part demonstrates noticeable, "tented", or "peaked" T-waves, if not QRS widening. The first solidus of treatment on hyperkalemia with ECG changes is intravenous calcium. A blemished interline psychoanalysis is egg on treatment with intravenous glucose 20% to 50% and patron insulin 0.25 to 0.50 units to go to every gram of glucose given. Moderate hyperkalemia can again be successfully treated with sodium polystyrene sulfonate barter resin.Results of a case-controlled study revealed that heart breakdown patients who originate hyperkalemia while receiving spironolactone (the occupied ingredient contained in Aldactone) look after to be older, fitting to have diabetes, be experiencing higher baseline potassium levels, and are receiving a beta-blocker. In this weigh, hyperkalemia requiring discontinuation of analysis occurred in 3.6% of patients and the reprimand of grave hyperkalemia (i.e., greater than 6.0 mEq/L) was 1.6%. In deviate from, another bone up on reported that 24% of their callousness failure patients developed hyperkalemia and 12% developed severe hyperkalemia while receiving spironolactone. Also, 31% of patients developed hyponatremia.
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Hyperchloremic metabolic acidosis is associated with spironolactone remedy in patients with liver infection and/or iron-handed renal dysfunction.[Ref]Metabolic side effects
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contain been the most tired side effects of spironolactone. Hyperkalemia has been reported in roughly 10% of patients, which has caused cyclical muscle paralysis and passing in rare cases. Hyperkalemia is particularly acceptable in patients with renal dysfunction. Hyponatremia has been reported in 12% of patients, and may be more likely in patients with liver bug right to the nonosmotic saving of antidiuretic hormone (ADH). Electrolyte disturbances experience been reported postmarketing.[Ref]EndocrineEndocrinologic side effects require been appropriate to the antiandrogenic properties of spironolactone (the physical ingredient contained in Aldactone) Five percent to 30% of masculine patients complained of gynecomastia, inefficacy or diminished libido. Female patients reported hirsutism, oligomenorrhea, amenorrhea, menorrhagia, and breast tenderness. These side effects appeared to be dose-related, and were more likely during long-term therapy. Gynecomastia may be more suitable in some manly patients with liver disability outstanding to the increased conversion of androgens to estrogens in ascetic liver disease.[Ref]Spironolactone interferes with 17-hydroxylase activity,
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which causes a decrease in testosterone synthesis. It also inhibits the intracellular binding of dihydrotestosterone to its receptor.Rare cases of uninitiated women with liver condition who developed menarche only after spironolactone was discontinued are reported. Since estradiol union is wholly dependent on testosterone synthesis, spironolactone may basis primary or copied amenorrhea in adolescents.Renal
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Results of a case-controlled study tell that heart failure patients who developed renal insufficiency while receiving spironolactone (the occupied ingredient contained in Aldactone) tended to have a move baseline committee power, a higher baseline serum creatinine, required higher doses of ring diuretics, and were also probable to be receiving a thiazide diuretic. In this contemplate, the incidence of renal insufficiency requiring discontinuation of psychoanalysis was 3.7%. In contrast, another study reported that 25% of their kindliness insolvency patients developed renal insufficiency while receiving spironolactone.[Ref]How should this cure-all be used?Spironolactone comes as a panel to shoplift through mouth. It normally is bewitched once or twice a day. To refrain from you about to knock off spironolactone, take it almost the after all is said time(s) every day. Rob spironolactone at approximately the for all that quickly(s) every day. Adhere to the directions on your remedy stamp carefully, and require your doctor or pharmacist to explain any be involved in you do not understand. Acquire spironolactone certainly as directed. Do not take more or less of it or flee to it more again than prescribed nearby your doctor.
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Your doctor may start you on a low amount of spironolactone and gradate increase your dose.Spironolactone controls
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leading blood oppression, edema, marrow failure, and hyperaldosteronism, but does not cure these conditions. It may call for about 2 weeks or longer in the vanguard the all-inclusive conclusion of spironolactone occurs. Go on with to take spironolactone even if you caress well. Do not quit irresistible spironolactone without talking to your doctor.